ENTRY       EC 3.4.24.12
NAME        Envelysin
            Sea-urchin-hatching proteinase
            Hatching enzyme
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Metalloendopeptidases
REACTION    Hydrolysis of proteins of the fertilization envelope and
            dimethylcasein.
SUBSTRATE   Protein
            Peptide
            H2O
PRODUCT     Protein
            Peptide
COFACTOR    Metal
COMMENT     A glycoprotein from various members of the class Echinoidea.
            Extracellular enzyme requiring Ca2+. A homologue of interstitial
            collagenase.
MOTIF       PS: PS00142  [GSTALIVN]-x(2)-H-E-[LIVMFYW]-{DEHRKP}-H-x-
                         [LIVMFYWGSPQ]
            PS: PS00546  P-R-C-[GN]-x-P-[DR]-[LIVSAP]
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.24.12
            WIT (What Is There) Metabolic Reconstruction: 3.4.24.12
///