ENTRY       EC 3.4.23.34
NAME        Cathepsin E
            Slow-moving proteinase
            Erythrocyte membrane aspartic proteinase
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Aspartic endopeptidases
REACTION    Similar to cathepsin D, but slightly broader specificity
SUBSTRATE   Protein
            Peptide
            H2O
PRODUCT     Protein
            Peptide
COMMENT     Found in stomach, spleen, erythrocyte membrane; not lysosomal.
            Pro-cathepsin E is an 86 kDa disulfide-linked dimer; activation
            or reduction produces monomer.
DISEASE     MIM: 116890  Cathepsin E
MOTIF       PS: PS00141  [LIVMFGAC]-[LIVMTADN]-[LIVFSA]-D-[ST]-G-[STAV]-
                         [STAPDENQ]-x-[LIVMFSTNC]-x-[LIVMFGTA]
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.23.34
            WIT (What Is There) Metabolic Reconstruction: 3.4.23.34
///