ENTRY       EC 3.4.23.29
NAME        Polyporopepsin
            Polyporus aspartic proteinase
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Aspartic endopeptidases
REACTION    Milk clotting activity, broad specificity, but fails to cleave
            Leu15-Tyr or Tyr16-Leu of insulin B chain.
SUBSTRATE   Protein
            Peptide
            H2O
PRODUCT     Protein
            Peptide
COMMENT     From the basidiomycete Polyporus tulipiferae (formerly Irpex
            lacteus).  A homologue of pepsin A.
MOTIF       PS: PS00141  [LIVMFGAC]-[LIVMTADN]-[LIVFSA]-D-[ST]-G-[STAV]-
                         [STAPDENQ]-x-[LIVMFSTNC]-x-[LIVMFGTA]
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.23.29
            WIT (What Is There) Metabolic Reconstruction: 3.4.23.29
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