ENTRY       EC 3.4.23.23
NAME        Mucorpepsin
            Mucor rennin
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Aspartic endopeptidases
REACTION    Hydrolysis of proteins, favouring hydrophobic residues at P1 and
            P1'.  Clots milk.  Does not accept Lys at P1, and hence does not
            activate trypsinogen
SUBSTRATE   Protein
            Peptide
            Casein
            H2O
PRODUCT     Protein
            Peptide
COMMENT     Isolated from the zygomycete fungi Mucor pusillus and M. miehei.
            The two species variants show 83�㿐�equence identity and are
            immunologically crossreactive.  Formerly included in EC 3.4.23.6.
MOTIF       PS: PS00141  [LIVMFGAC]-[LIVMTADN]-[LIVFSA]-D-[ST]-G-[STAV]-
                         [STAPDENQ]-x-[LIVMFSTNC]-x-[LIVMFGTA]
STRUCTURES  PDB: 1MPP  2ASI  
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.23.23
            WIT (What Is There) Metabolic Reconstruction: 3.4.23.23
            SCOP (Structural Classificaion of Proteins): 3.4.23.23
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