ENTRY       EC 3.4.22.8
NAME        Clostripain
            Clostridiopeptidase B
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Cysteine endopeptidases
REACTION    Preferential cleavage: Arg+, including Arg+Pro, but not Lys-
SUBSTRATE   Protein
            Peptide
            H2O
PRODUCT     Protein
            Peptide
COFACTOR    Calcium
INHIBITOR   N2-Acylated Arg-CH2Cl
            N2-Acylated Lys-CH2Cl
            EDTA
COMMENT     From the bacterium Clostridium histolyticum.  It requires Ca2+
            ions and is inhibited by EDTA.  Not a homologue of papain.
            Formerly EC 3.4.4.20.
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.22.8
            WIT (What Is There) Metabolic Reconstruction: 3.4.22.8
///