ENTRY EC 3.4.22.31
NAME Ananain
CLASS Hydrolases
Acting on peptide bonds (peptidases)
Cysteine endopeptidases
REACTION Hydrolysis of proteins with broad specificity for peptide bonds.
Best reported small molecule substrate Bz-Phe-Val-Arg+NHMec, but
broader specificity than fruit bromelain.
SUBSTRATE Protein
Peptide
H2O
PRODUCT Protein
Peptide
COMMENT From stem of pineapple plant, Ananas comosus. Differs from stem
and fruit bromelains in being inhibited by chicken cystatin.
DBLINKS University of Geneva ENZYME DATA BANK: 3.4.22.31
WIT (What Is There) Metabolic Reconstruction: 3.4.22.31
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