ENTRY       EC 3.4.22.30
NAME        Caricain
            Papaya peptidase A
            Papaya peptidase II
            Papaya proteinase Q
            Papaya proteinase III
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Cysteine endopeptidases
REACTION    Hydrolysis of proteins with broad specificity for peptide bonds,
            similar to those of papain and chymopapain
SUBSTRATE   Protein
            Peptide
            H2O
PRODUCT     Protein
            Peptide
COMMENT     From the papaya plant, Carica papaya.
MOTIF       PS: PS00139  Q-x(3)-[GE]-x-C-[YW]-x(2)-[STAGC]-[STAGCV]
            PS: PS00639  [LIVMGSTAN]-x-H-[GSACE]-[LIVM]-x-[LIVMAT](2)-G-x-
                         [GSADNH]
            PS: PS00640  [FYCH]-[WI]-[LIVT]-x-[KRQAG]-N-[ST]-W-x(3)-[FYW]-G-
                         x(2)-G-[LFYW]-[LIVMFYG]-x-[LIVMF]
STRUCTURES  PDB: 1MEG  1PPO  
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.22.30
            WIT (What Is There) Metabolic Reconstruction: 3.4.22.30
            SCOP (Structural Classificaion of Proteins): 3.4.22.30
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