ENTRY EC 3.4.22.29
NAME Picornain 2A
Picornavirus endopeptidase 2A
Poliovirus protease 2A
Rhinovirus protease 2A
CLASS Hydrolases
Acting on peptide bonds (peptidases)
Cysteine endopeptidases
REACTION Selective cleavage of Tyr+Gly bond in picornavirus polyprotein.
SUBSTRATE Picornavirus polyprotein
H2O
PRODUCT Protein
COMMENT From entero-, rhino-, aphto- and cardioviruses. Smaller than the
homologous picornain 3C, but not a homologue of papain.
DBLINKS University of Geneva ENZYME DATA BANK: 3.4.22.29
WIT (What Is There) Metabolic Reconstruction: 3.4.22.29
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