ENTRY       EC 3.4.21.9
NAME        Enteropeptidase
            Enterokinase
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Serine endopeptidases
REACTION    Activation of trypsinogen by selective cleavage of Lys6+Ile bond
SUBSTRATE   Trypsinogen
            H2O
PRODUCT     Trypsin
COMMENT     Is not inhibited by protein inhibitors of trypsin.  A homologue of
            chymotrypsin. Formerly EC 3.4.4.8.
DISEASE     MIM: 226200  Protease, serine, 7 (enterokinase); Enterokinase
                         deficiency (1)
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.21.9
            WIT (What Is There) Metabolic Reconstruction: 3.4.21.9
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