ENTRY       EC 3.4.21.64
NAME        Endopeptidase K
            Tritirachium alkaline proteinase
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Serine endopeptidases
REACTION    Hydrolysis of keratin, and of other proteins with subtilisin-like
            specificity.  Hydrolyses peptide amides
SUBSTRATE   Protein
            Peptide
            H2O
PRODUCT     Protein
            Peptide
COMMENT     From the mould Tritirachium album Limber.  A homologue of
            subtilisin containing two disulfide bridges and one free Cys near
            the active site His.  Formerly included in EC 3.4.21.14.
MOTIF       PS: PS00136  [STAIV]-x-[LIVMF]-[LIVM]-D-[DSTA]-G-[LIVMFC]-x(2,3)-
                         [DNH]
            PS: PS00137  H-G-[STM]-x-[VC]-[STAG]-[GS]-x-[LIVMA]-[STAGCLV]-[SAGM]
            PS: PS00138  G-T-S-x-[SA]-x-P-x(2)-[STAVC]-[AG]
STRUCTURES  PDB: 3PRK  2PKC  1PTK  1PEK  
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.21.64
            WIT (What Is There) Metabolic Reconstruction: 3.4.21.64
            SCOP (Structural Classificaion of Proteins): 3.4.21.64
///