ENTRY EC 3.4.21.63
NAME Oryzin
Aspergillus alkaline proteinase
Aspergillopeptidase B
CLASS Hydrolases
Acting on peptide bonds (peptidases)
Serine endopeptidases
REACTION Hydrolysis of proteins with broad specificity, and of
Bz-Arg-OEt > Ac-Tyr-OEt. Does not hydrolyse peptide amides
SUBSTRATE Peptide
H2O
PRODUCT Peptide
COMMENT A subtilisin homologue, not containing cysteine, that is the
predominant extracellular alkaline endopeptidase of the mould
Aspergillus oryzae. Formerly EC 3.4.21.15, and included in
EC 3.4.21.14. Identical or closely related enzymes are produced
by A. flavus and A. sojae.
MOTIF PS: PS00136 [STAIV]-x-[LIVMF]-[LIVM]-D-[DSTA]-G-[LIVMFC]-x(2,3)-
[DNH]
PS: PS00137 H-G-[STM]-x-[VC]-[STAG]-[GS]-x-[LIVMA]-[STAGCLV]-[SAGM]
PS: PS00138 G-T-S-x-[SA]-x-P-x(2)-[STAVC]-[AG]
DBLINKS University of Geneva ENZYME DATA BANK: 3.4.21.63
WIT (What Is There) Metabolic Reconstruction: 3.4.21.63
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