ENTRY       EC 3.4.21.55
NAME        Venombin AB
            Bitis gabonica serine proteinase
            Gabonase
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Serine endopeptidases
REACTION    Selective cleavage at Arg+ bonds in fibrinogen to form fibrin and
            release fibfinopeptides A and B
SUBSTRATE   Fibrinogen
            H2O
PRODUCT     Fibrin
            Fibfinopeptides A
            Fibfinopeptides B
COMMENT     From the venom of the Gaboon viper Bitis gabonica. Activates
            Factor XIII.  Not inhibited by antithrombin III/heparin or
            hirudin, unlike EC 3.4.21.5.
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.21.55
            WIT (What Is There) Metabolic Reconstruction: 3.4.21.55
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