ENTRY       EC 3.4.21.54
NAME        gamma-Renin
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Serine endopeptidases
REACTION    Cleavage of the Leu+Leu bond in synthetic tetradecapeptide renin
            substrate (horse), to produce angiotensin I, but not active on
            natural angiotensinogen, unlike renin (EC 3.4.23.15).  Also
            hydrolyses Bz-Arg-p-nitroanilide
SUBSTRATE   N-Benzoyl-D-arginine-4-nitroanilide
            H2O
COMMENT     A member of the tissue kallikrein family, from submandibular
            glands of male mice.
MOTIF       PS: PS00134  [LIVM]-[ST]-A-[STAG]-H-C
            PS: PS00135  [DNSTAGC]-[GSTAPIMVQH]-x(2)-G-[DE]-S-G-[GS]-[SAPHV]-
                         [LIVMFYWH]-[LIVMFYSTANQH]
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.21.54
            WIT (What Is There) Metabolic Reconstruction: 3.4.21.54
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