ENTRY       EC 3.4.21.20
NAME        Cathepsin G
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Serine endopeptidases
REACTION    Preferential cleavage: Tyr+, Trp+, Phe+, Leu+
SUBSTRATE   Protein
            Peptide
            H2O
PRODUCT     Oligopeptide
            Peptide
COMMENT     From azurophil granules of polymorphonuclear leukocytes. A
            homologue of chymotrypsin.
DISEASE     MIM: 116830  Cathepsin G
MOTIF       PS: PS00134  [LIVM]-[ST]-A-[STAG]-H-C
            PS: PS00135  [DNSTAGC]-[GSTAPIMVQH]-x(2)-G-[DE]-S-G-[GS]-[SAPHV]-
                         [LIVMFYWH]-[LIVMFYSTANQH]
STRUCTURES  PDB: 1CGH  
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.21.20
            WIT (What Is There) Metabolic Reconstruction: 3.4.21.20
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