ENTRY       EC 3.4.21.12
NAME        alpha-Lytic endopeptidase
            Myxobacter alpha-lytic proteinase
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Serine endopeptidases
REACTION    Preferential cleavage: Ala+, Val+ in bacterial cell walls, elastin
            and other proteins
SUBSTRATE   Protein alanine
            Peptide
            H2O
PRODUCT     Oligopeptide
            Peptide
COMMENT     From the myxobacterium Lysobacter enzymogenes.  A homologue of
            chymotrypsin.
MOTIF       PS: PS00134  [LIVM]-[ST]-A-[STAG]-H-C
            PS: PS00135  [DNSTAGC]-[GSTAPIMVQH]-x(2)-G-[DE]-S-G-[GS]-[SAPHV]-
                         [LIVMFYWH]-[LIVMFYSTANQH]
STRUCTURES  PDB: 1P04  1GBI  1GBH  1GBJ  1GBK  1GBA  1GBB  1GBF  1GBE  1GBD  
                 1GBL  1GBM  1P01  1P02  1P03  1GBC  1P05  1P06  1P09  1P10  
                 1P11  1P12  1TAL  2ALP  2LPR  2ULL  3LPR  5LPR  6LPR  7LPR  
                 8LPR  9LPR  
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.21.12
            WIT (What Is There) Metabolic Reconstruction: 3.4.21.12
            SCOP (Structural Classificaion of Proteins): 3.4.21.12
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