ENTRY EC 3.4.19.7
NAME N-Formylmethionyl-peptidase
(fMet)-releasing enzyme
CLASS Hydrolases
Acting on peptide bonds (peptidases)
Omega peptidases
REACTION Release of an N-terminal, formyl-methionyl residue from a
polypeptide
SUBSTRATE Peptide
H2O
PRODUCT Formyl-methionine
Peptide
INHIBITOR Heavy metal
EFFECTOR Chloride
COMMENT Highly specific for N-formylmethionyl peptides. Will not cleave
methionyl peptides or N-formyl derivatives of amino acids other
than methionine. Isolated from rat liver. Inhibited by heavy
metals and activated by Cl-.
DBLINKS University of Geneva ENZYME DATA BANK: 3.4.19.7
WIT (What Is There) Metabolic Reconstruction: 3.4.19.7
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