ENTRY       EC 3.4.19.10
NAME        Acylmuramoyl-Ala peptidase
            Acylmuramoyl-alaninase
            Acylmuramoyl-alanine carboxypeptidase
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Omega peptidases
REACTION    Cleavage of the N-acylmuramoyl+L-alanine bond
SUBSTRATE   Peptide
            H2O
PRODUCT     N-Acylmuramate
            Peptide
EFFECTOR    Divalent cation
COMMENT     This enzyme from Bacillus Bacillus megaterium and B. subtilis has
            a high affinity for the amide bonds formed between the amino
            sugar, acylmuramic acid and alanine in the bacterial cell wall.
            Cleavage of these bonds contributes to lysis of the cell wall.
            Activity is stimulated by divalent cations. Formerly EC 3.4.12.5
            and 3.4.17.7. The N-acylmuramoyl+alanine bond is also cleaved by
            beta-lytic metalloendopeptidase, EC 3.4.24.32.
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.19.10
            WIT (What Is There) Metabolic Reconstruction: 3.4.19.10
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