ENTRY EC 3.4.18.1
NAME Cysteine-type carboxypeptidase
Lysosomal carboxypeptidase B
Cathepsin B2
Cathepsin IV
Acid carboxypeptidase
CLASS Hydrolases
Acting on peptide bonds (peptidases)
Cysteine-type carboxypeptidases
REACTION Liberation of C-terminal amino acid residues, with broad
specificity, but lacks action on C-terminal proline
SUBSTRATE Peptide
H2O
PRODUCT Amino acid
Peptide
COMMENT Deaminates Z-Arg-NH2, but slows no action on the arylamide
derivatives. Inhibited by thiol-blocking reagents. Formerly
included with EC 3.4.16.1.
DBLINKS University of Geneva ENZYME DATA BANK: 3.4.18.1
WIT (What Is There) Metabolic Reconstruction: 3.4.18.1
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