ENTRY EC 3.4.17.17
NAME Tubulinyl-Tyr carboxypeptidase
Carboxypeptidase-tubulin
Soluble carboxypeptidase
CLASS Hydrolases
Acting on peptide bonds (peptidases)
Metallocarboxypeptidases
REACTION Cleavage of the -Glu+Tyr bond to release the C-terminal tyrosine
residue from the native tyrosinated tubulin. Inactive on
Z-Glu-Tyr
SUBSTRATE Peptide
H2O
PRODUCT Peptide
COMMENT Active at neutral pH, from brain.
DBLINKS University of Geneva ENZYME DATA BANK: 3.4.17.17
WIT (What Is There) Metabolic Reconstruction: 3.4.17.17
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