ENTRY EC 3.4.17.14
NAME Zinc D-Ala-D-Ala carboxypeptidase
Zn2+ G peptidase
D-Alanyl-D-alanine hydrolase
CLASS Hydrolases
Acting on peptide bonds (peptidases)
Metallocarboxypeptidases
REACTION Cleavage of the bond: (Ac)2-L-lysyl-D-alanyl+D-alanine
SUBSTRATE (Ac)2-L-lysyl-D-alanyl-D-alanine
H2O
PRODUCT (Ac)2-L-lysyl-D-alanine
D-Alanine
EFFECTOR Zinc
COMMENT A zinc enzyme. Catalyses carboxypeptidation but not
transpeptidation reactions involved in bacterial cell wall
metabolism. Weakly inihibited by beta-lactams. Distinct from
serine-type D-Ala-D-Ala carboxypepetidase, EC 3.4.16.4.
DBLINKS University of Geneva ENZYME DATA BANK: 3.4.17.14
WIT (What Is There) Metabolic Reconstruction: 3.4.17.14
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