ENTRY EC 3.4.14.4
NAME Dipeptidyl peptidase III
Dipeptidyl aminopeptidase III
Dipeptidyl arylamidase III
Red cell angiotensinase
Enkephalinase B
CLASS Hydrolases
Acting on peptide bonds (peptidases)
Dipeptidyl-peptidases and tripeptidyl-peptidases
REACTION Release of an N-terminal dipeptide from a peptide of four or more
residues, with broad specificity.
SUBSTRATE Peptide
H2O
PRODUCT Dipeptide
Peptide
COMMENT A cytosolic serine-type peptidase active at neutral pH. Highly
selective for Arg-Arg-2-naphthylamide at pH 9.2. Inactive on
(Glu)4, (Gly)4, and tripeptides, as well as bonds involving
proline.
DBLINKS University of Geneva ENZYME DATA BANK: 3.4.14.4
WIT (What Is There) Metabolic Reconstruction: 3.4.14.4
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