ENTRY EC 3.4.14.2
NAME Dipeptidyl-peptidase II
Dipeptidyl aminopeptidase II
Dipeptidyl arylamidase II
Carboxytripeptidase
CLASS Hydrolases
Acting on peptide bonds (peptidases)
Dipeptidyl-peptidases and tripeptidyl-peptidases
REACTION Release of an N-terminal dipeptide, Xaa-Xbb+, preferentially when
Xbb is Als or Pro. substrates are oligopeptides, preferentially
tripeptides.
SUBSTRATE Tripeptide
H2O
PRODUCT Dipeptide
Amino acid
COMMENT A lysosomal serine-type peptidase maximally active at acidic pH.
DBLINKS University of Geneva ENZYME DATA BANK: 3.4.14.2
WIT (What Is There) Metabolic Reconstruction: 3.4.14.2
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