ENTRY EC 3.4.13.5
NAME X-Methyl-His dipeptidase
Anserinase
Aminoacyl-methylhistidine dipeptidase
Acetylhistidine deacetylase
CLASS Hydrolases
Acting on peptide bonds (peptidases)
Dipeptidases
REACTION Hydrolysis of anserine (beta-alanyl-N(pai)-methyl-L-histidine),
carnosine, homocarnosine, glycyl-leucine and other dipeptides with
broad specificity.
SUBSTRATE beta-Alanyl-N(pai)-methyl-L-histidine
Carnosine
Homocarnosine
Glycyl-leucine
Dipeptide
H2O
PRODUCT beta-Alanine
N(pai)-Methyl-L-histidine
L-Histidine
4-Aminobutylate
Glycine
L-Leucine
Amino acid
COMMENT Is identical with acetylhistidine deacetylase (formerly
EC 3.5.1.34). formerly EC 3.4.3.4.
PATHWAY PATH: MAP00340 Histidine metabolism
PATH: MAP00410 beta-Alanine metabolism
DBLINKS University of Geneva ENZYME DATA BANK: 3.4.13.5
WIT (What Is There) Metabolic Reconstruction: 3.4.13.5
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