ENTRY EC 3.4.11.3
NAME Cystinyl aminopeptidase
Cystyl-aminopeptidase
Oxytocinase
Cystine aminopeptidase
CLASS Hydrolases
Acting on peptide bonds (peptidases)
Aminopeptidases
REACTION Release of an N-terminal amino acid, Cys+Xaa, in which the half-
-cystine residue is involved in a disulfide loop, notably in
oxytocin or vasopressin. Hydrolysis rates on a range of aminoacyl
arylamides exceed that for the cystinyl derivative.
SUBSTRATE Oxytocin
Vasopressin
H2O
PRODUCT L-Cysteine
Oligopeptide
COFACTOR Zinc
COMMENT A zinc-containing sialoglycoprotein.
DBLINKS University of Geneva ENZYME DATA BANK: 3.4.11.3
WIT (What Is There) Metabolic Reconstruction: 3.4.11.3
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