ENTRY       EC 3.4.11.16
NAME        X-Trp aminopeptidase
            Aminopeptidase W
            Aminopeptidase X-Trp
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Aminopeptidases
REACTION    Release of a variety of N-terminal residues (especially glutamate
            and leucine) from peptides, provided tryptophan (or at least
            phenylalanine or tyrosine) is the penultimate residue. Also acts
            on Glu+Trp, Leu+Trp and a number of other dipeptides.
SUBSTRATE   Peptide
            X-Trp
            H2O
PRODUCT     L-Glutamate
            L-Leucine
            Peptide
            Tryptophan
COMMENT     A glycoprotein containing Zn2+, from renal and intestinal brush
            border membranes.
GENES       HSA: XWNPEP
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.11.16
            WIT (What Is There) Metabolic Reconstruction: 3.4.11.16
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