ENTRY       EC 3.4.11.15
NAME        Lysyl aminopeptidase
            Aminopeptidase Co
            Aminopeptidase (cobalt-activated)
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Aminopeptidases
REACTION    Release of N-terminal lysine
SUBSTRATE   Peptide
            H2O
PRODUCT     L-Lysine
            Peptide
INHIBITOR   Zinc
            Manganese
COFACTOR    Cobalt
COMMENT     Requires Co2+; inhibited by Zn2+ and Mn2+. An enzyme from
            Saccharomyces cerevisiae that hydrolyses L-lysyl-4-nitroanilide
            and, more slowly, L-arginyl-4-nitroanilide.
GENES       HSA: KNPEP
DBLINKS     University of Geneva ENZYME DATA BANK: 3.4.11.15
            WIT (What Is There) Metabolic Reconstruction: 3.4.11.15
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