ENTRY EC 3.4.11.14
NAME Cytosol alanyl aminopeptidase
Arylamidase
Aminopolypeptidase
Thiol-activated aminopeptidase
Human liver aminopeptidase
Puromycin-sensitive aminopeptidase
Soluble alanyl aminopeptidase
Cytosol aminopeptidase III
CLASS Hydrolases
Acting on peptide bonds (peptidases)
Aminopeptidases
REACTION Release of an N-terminal amino acid, preferentially alanine, from
a wide range of peptides, amides and arylamides.
SUBSTRATE Peptide
Amide
Arylamide
H2O
PRODUCT L-Alanine
Peptide
COFACTOR Cobalt
Zinc
COMMENT A puromycin-sensitive, Co2+-activated zinc-sialoglycoprotein that
is generally cytosolic. Multiple forms are widely distributed in
mammalian tissues and body fluids.
DBLINKS University of Geneva ENZYME DATA BANK: 3.4.11.14
WIT (What Is There) Metabolic Reconstruction: 3.4.11.14
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