ENTRY       EC 3.3.2.7
NAME        Hepoxilin-epoxide hydrolase
CLASS       Hydrolases
            Acting on ether bonds
            Ether hydrolases
SYSNAME     (5Z,9E,14Z)-(8xi,11R,12S)-11,12-Epoxy-8-hydroxyicosa-5,9,14-
            $trienoate hydrolase
REACTION    (5Z,9E,14Z)-(8xi,11R,12S)-11,12-Epoxy-8-hydroxyeicosa-5,9,14-
            $trienoate + H2O = (5Z,9E,14Z)-(8xi,11xi,12S)-8,11,12-
            $Trihydroxyeicosa-5,9,14-trienoate
SUBSTRATE   (5Z,9E,14Z)-(8xi,11R,12S)-11,12-Epoxy-8-hydroxyeicosa-5,9,14-
            $trienoate
            H2O
            Hepoxilin A3
PRODUCT     (5Z,9E,14Z)-(8xi,11xi,12S)-8,11,12-Trihydroxyeicosa-5,9,14-
            $trienoate
            Trioxilin A3
COMMENT     Converts hepoxilin A3 into trioxilin A3. Highly specific. Not
            identical with EC 3.3.2.6.
DBLINKS     University of Geneva ENZYME DATA BANK: 3.3.2.7
            WIT (What Is There) Metabolic Reconstruction: 3.3.2.7
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