ENTRY       EC 3.3.1.1
NAME        Adenosylhomocysteinase
CLASS       Hydrolases
            Acting on ether bonds
            Thioether hydrolases
SYSNAME     S-Adenosyl-L-homocysteine hydrolase
REACTION    S-Adenosyl-L-homocysteine + H2O = Adenosine + L-Homocysteine
SUBSTRATE   S-Adenosyl-L-homocysteine
            H2O
PRODUCT     Adenosine
            L-Homocysteine
PATHWAY     PATH: MAP00271  Methionine metabolism
            PATH: MAP00450  Selenoamino acid metabolism
DISEASE     MIM: 180960  S-adenosylhomocysteine hydrolase
MOTIF       PS: PS00738  C-N-I-[FY]-S-[ST]-Q-[DEN]-x-A-A-A-A-I-A
            PS: PS00739  G-K-x(3)-[LIV]-x-G-Y-G-D-V-G-K-G
GENES       MJA: MJ1388
            MTH: MTH1636
            SYN: sll1234(ahcY)
            SCE: YER043C(SAH1)
            HSA: AHCY(Hs.85111)
DBLINKS     University of Geneva ENZYME DATA BANK: 3.3.1.1
            WIT (What Is There) Metabolic Reconstruction: 3.3.1.1
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