ENTRY       EC 3.2.2.5
NAME        NAD+ nucleosidase
            NADase
            DPNase
            DPN hydrolase
CLASS       Hydrolases
            Glycosidases
            Hydrolysing N-glycosyl compounds
SYSNAME     NAD+ glycohydrolase
REACTION    NAD+ + H2O = Nicotinamide + ADPribose
SUBSTRATE   NAD+
            H2O
PRODUCT     Nicotinamide
            ADPribose
COMMENT     The enzyme from some animal sources also catalyses transfer of
            ADPribose residues.
PATHWAY     PATH: MAP00760  Nicotinate and nicotinamide metabolism
DISEASE     MIM: 107270  CD38 antigen (p45); ADP-ribosyl cyclase/cyclic
                         ADP-ribose hydrolase
            MIM: 600387  Bone marrow stromal cell antigen 1
DBLINKS     University of Geneva ENZYME DATA BANK: 3.2.2.5
            WIT (What Is There) Metabolic Reconstruction: 3.2.2.5
///