ENTRY       EC 3.2.2.21
NAME        DNA-3-methyladenine glycosidase II
CLASS       Hydrolases
            Glycosidases
            Hydrolysing N-glycosyl compounds
SYSNAME     Alkylated-DNA glycohydrolase (releasing methyladenine and
            methylguanine)
REACTION    Hydrolysis of alkylated DNA, releasing 3-methyladenine,
            3-methylguanine, 7-methylguanine and 7-methyladenine.
SUBSTRATE   Alkylated DNA
            H2O
PRODUCT     3-Methyladenine
            3-Methylguanine
            7-Methylguanine
            7-Methyladenine
COMMENT     Involved in the removal of alkylated bases from DNA in
            Escherichia coli (cf. EC 2.1.1.63).
DISEASE     MIM: 156565  N-methylpurine DNA glycosylase
MOTIF       PS: PS00516  G-I-G-x-W-[ST]-A-x-[LIVMFY](2)-x-[LIVM]-x(8)-F-x(2)-
                         [ED]-D
GENES       ECO: b2068(alkA)
            BSU: alkA yfjP
            SYN: slr0231
            SCE: YER142C(MAG1)
DBLINKS     University of Geneva ENZYME DATA BANK: 3.2.2.21
            WIT (What Is There) Metabolic Reconstruction: 3.2.2.21
///