ENTRY EC 3.2.1.96
NAME Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
N,N'-Diacetylchitobiosyl beta-N-acetylglucosaminidase
Endo-beta-N-acetylglucosaminidase
CLASS Hydrolases
Glycosidases
Hydrolysing O-glycosyl compounds
SYSNAME Glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-
-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase
REACTION Endohydroylsis of the N,N'-diacetylchitobiosyl unit in
high-mannose glycopeptides and glycoproteins containing the
-[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue
remains attached to the protein; the rest of the oligosaccharide
is released intact
SUBSTRATE High-mannose glycopeptide containing -{Man(GlcNAc)2}Asn-
H2O
PRODUCT Oligosaccharide(terminal -ManGlcNAc)
N-Acetyl-D-glucosamine
COMMENT A group of related enzymes.
MOTIF PS: PS01095 [LIVMFY]-[DN]-G-[LIVMF]-[DN]-[LIVMF]-[DN]-x-E
STRUCTURES PDB: 1EDT 2EBN
DBLINKS University of Geneva ENZYME DATA BANK: 3.2.1.96
WIT (What Is There) Metabolic Reconstruction: 3.2.1.96
SCOP (Structural Classificaion of Proteins): 3.2.1.96
///
DBGET integrated database retrieval system,
GenomeNet