ENTRY       EC 3.2.1.76
NAME        L-Iduronidase
CLASS       Hydrolases
            Glycosidases
            Hydrolysing O-glycosyl compounds
SYSNAME     Glycosaminoglycan alpha-L-iduronohydrolase
REACTION    Hydrolysis of unsulfated alpha-L-iduronosidic linkages in
            dermatan sulfate
SUBSTRATE   Dermatan sulfate
            H2O
PRODUCT     Dermatan sulfate
DISEASE     MIM: 252800  Iduronidase, alpha-L-; Mucopolysaccharidosis Ih (3);
                         Mucopolysaccharidosis Is (3); Mucopolysaccharidosis
                         Ih/s (3)
MOTIF       PS: PS01027  W-x-F-E-x-W-N-E-P-[DN]
GENES       HSA: IDUA(Hs.89560)
DBLINKS     University of Geneva ENZYME DATA BANK: 3.2.1.76
            WIT (What Is There) Metabolic Reconstruction: 3.2.1.76
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