ENTRY       EC 3.2.1.45
NAME        Glucosylceramidase
            Psychosine hydrolase
            Glucosphingosine glucosylhydrolase
CLASS       Hydrolases
            Glycosidases
            Hydrolysing O-glycosyl compounds
SYSNAME     D-Glucosyl-N-acylsphingosine glucohydrolase
REACTION    D-Glucosyl-N-acylsphingosine + H2O = D-Glucose + N-Acylsphingosine
SUBSTRATE   D-Glucosyl-N-acylsphingosine
            H2O
PRODUCT     D-Glucose
            N-Acylsphingosine
COMMENT     Also acts on glucosylsphingosine
            (cf. EC 3.2.1.62: Glycosylceramidase).
PATHWAY     PATH: MAP00600  Sphingoglycolipid metabolism
DISEASE     MIM: 230800  Glucosidase, beta; acid; Gaucher disease (3); Gaucher
                         disease with cardiovascular calcification (3)
DBLINKS     University of Geneva ENZYME DATA BANK: 3.2.1.45
            WIT (What Is There) Metabolic Reconstruction: 3.2.1.45
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