ENTRY       EC 3.2.1.33
NAME        Amylo-1,6-glucosidase
            Dextrin 6-alpha-D-glucosidase
CLASS       Hydrolases
            Glycosidases
            Hydrolysing O-glycosyl compounds
SYSNAME     Dextrin 6-alpha-D-glucanohydrolase
REACTION    Endohydrolysis of 1,6-alpha-D-glucoside linkages at points of
            branching in chains of 1,4-linked-alpha-D-glucose residues
SUBSTRATE   Glycogen
            H2O
            Amylopectin
PRODUCT     Glycogen
            Amylopectin
COMMENT     In mammals and yeast this enzyme is linked to a glycosyl
            transferase similar to EC 2.4.1.25; together these two activities
            constitute the glycogen debranching system.
PATHWAY     PATH: MAP00500  Starch and sucrose metabolism
DISEASE     MIM: 232400  Amylo-1,6-glucosidase, 4-alpha-glucanotransferase
                         (glycogen; Glycogen storage disease IIIa (1); Glycogen
                         storage disease IIIb (3)
DBLINKS     University of Geneva ENZYME DATA BANK: 3.2.1.33
            WIT (What Is There) Metabolic Reconstruction: 3.2.1.33
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