ENTRY       EC 3.2.1.24
NAME        alpha-Mannosidase
CLASS       Hydrolases
            Glycosidases
            Hydrolysing O-glycosyl compounds
SYSNAME     alpha-D-Mannoside mannohydrolase
REACTION    Hydrolysis of terminal, non-reducing alpha-D-mannose residues in
            alpha-D-mannosides
SUBSTRATE   alpha-D-Mannoside
            H2O
            alpha-D-Lyxoside
            Heptopyranosides
PRODUCT     alpha-D-Mannose
            alpha-D-Lyxose
COMMENT     Also hydrolyses alpha-D-lyxosides and heptopyranosides with the
            same configuration at C-2, C-3 and C-4 as mannose.
DISEASE     MIM: 248500  Mannosidase, alpha B, lysosomal; Mannosidosis, alpha-
                         (3)
GENES       SYN: slr0323(ams1)
            SCE: YGL156W(AMS1)
            HSA: MANA1(MANA) MANB(Hs.89432)
DBLINKS     University of Geneva ENZYME DATA BANK: 3.2.1.24
            WIT (What Is There) Metabolic Reconstruction: 3.2.1.24
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