ENTRY EC 3.2.1.106
NAME Mannosyl-oligosaccharide glucosidase
CLASS Hydrolases
Glycosidases
Hydrolysing O-glycosyl compounds
SYSNAME Mannosyl-oligosaccharide glucohydrolase
REACTION Exohydrolsis of the non-reducing terminal glucose residues in the
mannosyl-oligosaccharide Glc3Man9GlcNAc2
SUBSTRATE Mannosyl-oligosaccharide Glc3Man9GlcNAc2
H2O
PRODUCT D-Glucose
COMMENT Also acts, more slowly, on the corresponding glycolipids and
glycopeptides. Involved in the formation of high-mannose and
complex glycoproteins.
PATHWAY PATH: MAP00510 Biosynthesis and degradation of glycoprotein
DISEASE MIM: 601336 Glucosidase I
DBLINKS University of Geneva ENZYME DATA BANK: 3.2.1.106
WIT (What Is There) Metabolic Reconstruction: 3.2.1.106
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