ENTRY       EC 3.1.6.18
NAME        Glucuronate-2-sulfatase
            Chondro-2-sulfatase
CLASS       Hydrolases
            Acting on ester bonds
            Sulfuric ester hydrolases
SYSNAME     Polysaccharide-2-O-sulfo-D-glucuronate 2-sulfohydrolase
REACTION    Hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate
            residues of chondroitin sulfate, heparin and heparitin sulfate
SUBSTRATE   Chondroitin sulfate
            Heparin
            Heparitin sulfate
            H2O
PRODUCT     Chondroitin sulfate
            Heparin
            Heparitin sulfate
            Sulfate
COMMENT     Does not act on iduronate 2-sulfate residues (cf. EC 3.1.6.13).
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.6.18
            WIT (What Is There) Metabolic Reconstruction: 3.1.6.18
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