ENTRY       EC 3.1.6.15
NAME        N-Sulfoglucosamine-3-sulfatase
            Chondroitinsulfatase
CLASS       Hydrolases
            Acting on ester bonds
            Sulfuric ester hydrolases
SYSNAME     N-Sulfo-3-sulfoglucosamine 3-sulfohydrolase
REACTION    Hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine
            3-O-sulfate units of heparin
SUBSTRATE   Heparin
            H2O
PRODUCT     Heparin
            Sulfate
COMMENT     The enzyme from Flavobacterium heparinum also hydrolyses
            N-acetyl-D-glucosamine 3-O-sulfate; the mammalian enzyme acts
            only on the disulfated residue.
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.6.15
            WIT (What Is There) Metabolic Reconstruction: 3.1.6.15
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