ENTRY       EC 3.1.4.50
NAME        Glycoprotein phospholipase D
CLASS       Hydrolases
            Acting on ester bonds
            Phosphoric diester hydrolases
SYSNAME     Glycoprotein-phosphatidylinositol phosphatidohydrolase
REACTION    Glycoprotein phosphatidylinositol + H2O = Phosphatidate +
            Glycoprotein inositol
SUBSTRATE   Glycoprotein phosphatidylinositol
            H2O
PRODUCT     Phosphatidate
            Glycoprotein inositol
COMMENT     By hydrolysis, degrades the glycosylphosphatidylinositol membrane
            anchor of cell-surface proteins in animal tissues, thus releasing
            these protein from the membrane. Not identical with EC 3.1.4.47.
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.4.50
            WIT (What Is There) Metabolic Reconstruction: 3.1.4.50
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