ENTRY EC 3.1.4.46
NAME Glycerophosphodiester phosphodiesterase
CLASS Hydrolases
Acting on ester bonds
Phosphoric diester hydrolases
SYSNAME Glycerophosphodiester glycerophosphohydrolase
REACTION a Glycerophosphodiester + H2O = an Alcohol +
sn-Glycerol 3-phosphate
SUBSTRATE Glycerophosphodiester
H2O
Glycerophosphocholine
Glycerophosphoethanolamine
Glycerophosphoglycerol
Bis(glycerophospho)-glycerol
PRODUCT Alcohol
sn-Glycerol 3-phosphate
Choline
Ethanolamine
Glycerol
Glycerophosphoglycerol
COMMENT Broad specificity for glycerophosphodiesters;
glycerophosphocholine, glycerophosphoethanolamine,
glycerophosphoglycerol, and bis(glycerophospho)-glycerol are
hydrolysed.
PATHWAY PATH: MAP00561 Glycerolipid metabolism
PATH: MAP00580 Phospholipid degradation
MOTIF PS: PS00013 {DERK}(6)-[LIVMFWSTAG](2)-[LIVMFYSTAGCQ]-[AGS]-C
GENES ECO: b2239(glpQ) b3449(ugpQ)
HIN: HI0689(glpQ)
BSU: glpQ(ybeD) yhdW
MPN: A05_orf241a(glpQ)
SYN: sll1236
DBLINKS University of Geneva ENZYME DATA BANK: 3.1.4.46
WIT (What Is There) Metabolic Reconstruction: 3.1.4.46
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