ENTRY       EC 3.1.4.45
NAME        N-Acetylglucosamine-1-phosphodiester
            $ alpha-N-acetylglucosaminidase
            alpha-N-Acetylglucosaminyl phosphodiesterase
            Lysosomal alpha-N-acetylglucosaminidase
CLASS       Hydrolases
            Acting on ester bonds
            Phosphoric diester hydrolases
SYSNAME     Glycoprotein-N-acetyl-D-glucosaminyl-phospho-D-mannose
            $ N-acetyl-D-glucosaminylphosphohydrolase
REACTION    Glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O =
            N-Acetyl-D-glucosamine + Glycoprotein phospho-D-mannose
SUBSTRATE   Glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose
            H2O
PRODUCT     N-Acetyl-D-glucosamine
            Glycoprotein phospho-D-mannose
COMMENT     Acts on a variety of compounds in which N-acetyl-D-glucosamine is
            alpha-linked to a phosphate group, including the biosynthetic
            intermediates of the high mannose oligosaccharide components of
            some lysosomal enzymes and the products of EC 2.7.8.17.
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.4.45
            WIT (What Is There) Metabolic Reconstruction: 3.1.4.45
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