ENTRY       EC 3.1.4.35
NAME        3',5'-Cyclic-GMP phosphodiesterase
CLASS       Hydrolases
            Acting on ester bonds
            Phosphoric diester hydrolases
SYSNAME     3',5'-Cyclic-GMP 5'-nucleotidohydrolase
REACTION    Guanosine 3',5'-cyclic phosphate + H2O = Guanosine 5'-phosphate
SUBSTRATE   Guanosine 3',5'-cyclic phosphate
            H2O
PRODUCT     Guanosine 5'-phosphate
DISEASE     MIM: 180071  Phosphodiesterase 6A, cGMP-specific, rod, alpha;
                         Retinitis pigmentosa, autosomal recessive (3)
            MIM: 180072  Phosphodiesterase 6B, cGMP-specific, rod, beta; Night
                         blindness, congenital stationary, type 3, 163500 (3)
            MIM: 180073  Phosphodiesterase 6G, cGMP-specific, rod, gamma
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.4.35
            WIT (What Is There) Metabolic Reconstruction: 3.1.4.35
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