ENTRY EC 3.1.4.35
NAME 3',5'-Cyclic-GMP phosphodiesterase
CLASS Hydrolases
Acting on ester bonds
Phosphoric diester hydrolases
SYSNAME 3',5'-Cyclic-GMP 5'-nucleotidohydrolase
REACTION Guanosine 3',5'-cyclic phosphate + H2O = Guanosine 5'-phosphate
SUBSTRATE Guanosine 3',5'-cyclic phosphate
H2O
PRODUCT Guanosine 5'-phosphate
DISEASE MIM: 180071 Phosphodiesterase 6A, cGMP-specific, rod, alpha;
Retinitis pigmentosa, autosomal recessive (3)
MIM: 180072 Phosphodiesterase 6B, cGMP-specific, rod, beta; Night
blindness, congenital stationary, type 3, 163500 (3)
MIM: 180073 Phosphodiesterase 6G, cGMP-specific, rod, gamma
DBLINKS University of Geneva ENZYME DATA BANK: 3.1.4.35
WIT (What Is There) Metabolic Reconstruction: 3.1.4.35
///
DBGET integrated database retrieval system,
GenomeNet