ENTRY       EC 3.1.4.16
NAME        2',3'-Cyclic-nucleotide 2'-phosphodiesterase
CLASS       Hydrolases
            Acting on ester bonds
            Phosphoric diester hydrolases
SYSNAME     Nucleoside-2',3'-cyclic-phosphate 3'-nucleotidohydrolase
REACTION    Nucleoside 2',3'-cyclic phosphate + H2O = Nucleoside 3'-phosphate
SUBSTRATE   Nucleoside 2',3'-cyclic phosphate
            3'-Nucleoside monophosphate
            Bis-4-nitrophenyl phosphate
            H2O
PRODUCT     Nucleoside 3'-phosphate
COMMENT     Also hydrolyses 3'-nucleoside monophosphates and bis-4-nitrophenyl
            phosphate, but not 3'-deoxynucleotides. Similar reactions are
            carried out by EC 3.1.27.3 and 3.1.27.5.
            (EC 3.1.27.3 Ribonuclease T1)
            (EC 3.1.27.5 Pancreatic ribonuclease)
MOTIF       PS: PS00785  [LIVM]-x-[LIVM](2)-[HEA]-[TI]-x-D-x-H-[GSA]
            PS: PS00786  [FY]-x(4)-[LIVM]-G-N-H-E-F-[DN]
GENES       ECO: b4213(cpdhtmB)
            HIN: HI0583(cpdhtmB)
            HPY: HP0104(cpdhtmB)
            BSU: yfkN
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.4.16
            WIT (What Is There) Metabolic Reconstruction: 3.1.4.16
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