ENTRY       EC 3.1.4.1
NAME        Phosphodiesterase I
            5'-Exonuclease
CLASS       Hydrolases
            Acting on ester bonds
            Phosphoric diester hydrolases
SYSNAME     Oligonucleate 5'-nucleotidohydrolase
REACTION    Hydrolytically removes 5'-nucleotides successively from the
            3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides
SUBSTRATE   3'-Hydroxy-terminated oligonucleotide
            H2O
PRODUCT     5'-Nucleotide
COMMENT     Low activity towards polynucleotides. A 3'-phosphate terminus on
            the substrate inhibits hydrolysis.
MOTIF       PS: PS00524  C-x-C-x(3)-C-x(5)-C-C-x-[DN]-[FY]-x(3)-C
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.4.1
            WIT (What Is There) Metabolic Reconstruction: 3.1.4.1
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