ENTRY EC 3.1.30.1
NAME Aspergillus nuclease S1
Endonuclease S1 (Aspergillus)
Single-stranded-nucleate endonuclease
Deoxyribonuclease S1
CLASS Hydrolases
Acting on ester bonds
Endonucleases active with either ribo- or deoxyribonucleic acids
and producing 5'-phosphomonoesters
REACTION Endonucleolytic cleavage to 5'-phosphomononucleotide and
5'-phosphooligonucleotide end-products
SUBSTRATE RNA
DNA
H2O
PRODUCT 5'-Phosphomononucleotide
5'-Phosphooligonucleotide
COMMENT Similar enzymes: N.crassa nuclease; Mung bean nuclease;
Penicillium citrinum nuclease P1. Preference for single-stranded
substrate. Formerly EC 3.1.4.21.
DBLINKS University of Geneva ENZYME DATA BANK: 3.1.30.1
WIT (What Is There) Metabolic Reconstruction: 3.1.30.1
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