ENTRY EC 3.1.27.9
NAME tRNA-intron endonuclease
CLASS Hydrolases
Acting on ester bonds
Endoribonucleases producing other than 5'-phosphomonoesters
REACTION Endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and
2',3'-cyclic phosphate termini, and specifically removing the
intron.
SUBSTRATE Pre-tRNA
H2O
PRODUCT 5'-Hydroxyoligoribonucleotide
2',3'-Cyclicphosphooligoribonucleotide
tRNA
COMMENT The enzyme catalyses the final stage in the maturation of tRNA
molecules.
DBLINKS University of Geneva ENZYME DATA BANK: 3.1.27.9
WIT (What Is There) Metabolic Reconstruction: 3.1.27.9
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