ENTRY       EC 3.1.27.1
NAME        Ribonuclease T2
            Ribonuclease II
CLASS       Hydrolases
            Acting on ester bonds
            Endoribonucleases producing other than 5'-phosphomonoesters
REACTION    Two-stage endonucleolytic cleavage to 3'-phosphomononucleotides
            and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate
            intermediate
SUBSTRATE   RNA
            H2O
PRODUCT     3'-Phosphomononucleotide
            3'-Phosphooligonucleotide
COMMENT     Similar enzymes: Plant RNase; E.coli RNase I; RNase N2;
            Microbial RNase II. Formerly EC 2.7.7.17 and 3.1.4.23.
MOTIF       PS: PS00530  [FYWL]-x-[LIVM]-H-G-L-W-P
            PS: PS00531  [LIVMF]-x(2)-[HDY]-[EQ]-[FYW]-x-[KR]-H-G-x-C
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.27.1
            WIT (What Is There) Metabolic Reconstruction: 3.1.27.1
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