ENTRY EC 3.1.26.5
NAME Ribonuclease P
CLASS Hydrolases
Acting on ester bonds
Endoribonucleases producing 5'-phosphomonoesters
REACTION Endonucleolytic cleavage of RNA, removing 5'-extranucleotides
from tRNA precursor.
SUBSTRATE RNA
H2O
PRODUCT RNA
COMMENT An RNA-containing enzyme, essential for tRNA processing; generates
5'-termini of mature tRNA molecules. Similar enzyme: RNase P3.
MOTIF PS: PS00648 [LIVMFY]-x(2)-A-x(2)-R-[NH]-[KRQL]-[LIVM]-[KRA]-R-x-
[LIVMTA]-[KR]
GENES ECO: b3704(rnpA)
HIN: HI0999(rnpA)
HPY: HP1448(rnpA)
BSU: rnpA
MGE: MG465(rnpA)
MPN: K05_orf118V(rnpA)
SYN: slr1469(rnpA)
SCE: YML091C(RPM2)
DBLINKS University of Geneva ENZYME DATA BANK: 3.1.26.5
WIT (What Is There) Metabolic Reconstruction: 3.1.26.5
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