ENTRY       EC 3.1.22.5
NAME        Deoxyribonuclease X
CLASS       Hydrolases
            Acting on ester bonds
            Endodeoxyribonucleases producing other than 5'-phosphomonoesters
REACTION    Endonucleolytic cleavage of supercoiled plasma DNA to linear DNA
            duplexes.
SUBSTRATE   Supercoiled plasma DNA
            H2O
PRODUCT     Linear DNA duplexes
INHIBITOR   Single-stranded DNA
            ATP
            AMP
COMMENT     Preference for supercoiled DNA; little activity on linear double-
            -stranded DNA. Inhibited by single-stranded DNA, ATP and AMP.
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.22.5
            WIT (What Is There) Metabolic Reconstruction: 3.1.22.5
///